Recent Advancements In IVF Technology | Reviva IVF

Infertility is a major issue in the world today, and IVF treatment has been a boon for those couples who are unable to conceive naturally. It involves fertilization of the egg and sperm outside the body in a laboratory, followed by its implantation into the woman’s uterus. After that, the embryo is obtained from the egg and sperm of the couple, or donated eggs and sperm can also be used in case of any issues in conception.

  

There have been incredible advancements in the field of IVF technology. However, as per the expert endocrinologist, sometimes complications can arise with in vitro fertilization which may affect the chances of pregnancy. Therefore, a thorough evaluation of the aforementioned medical conditions should be done to increase the odds of successful conception with ART (assisted reproductive technique). 

New methods and technologies are being developed to make this process more efficient and effective. Some of these advancements include:

Preimplantation Genetic Testing (PGT):

This test can be carried out on embryos before implanting them into the uterus. PGT can be done for chromosome abnormalities or single-gene disorders. The PGT uses Next-Generation Sequencing (NGS) technology and Comparative Genomic Hybridization (CGH) to analyze all 23 pairs of chromosomes present in each embryo. This helps in deciding the suitable embryo with good genetic quality, which will help in improving the chances of pregnancy through IVF treatment in Chandigarh or any other city.

Egg Vitrification

Egg vitrification is a method of cryopreservation that uses liquid nitrogen to preserve eggs. The process has been around since 2013, but only recently has it gained traction as a valuable tool for IVF clinics.

Eggs are particularly sensitive to the freezing process and can suffer damage from ice crystal formation. In the past, slow freezing was the only option available, but with slow freezing, there is a risk that ice crystals might form inside cells and kill them. This is why egg preservation has been reserved for women who are facing medical treatments that may leave them sterile or infertile.

Egg vitrification solves this problem by allowing the eggs to be plunged into liquid nitrogen in mere seconds. They are then preserved in a state of suspended animation until they are ready to be thawed and fertilized. After thawing, they have a survival rate of 97%.

Vitrification has made it easier for women to safely preserve their eggs until they are ready to conceive, which means more babies will be born using IVF technology in the near future.

PRISM

Most IVF cycles involve in vitro maturation (IVM) of eggs, which refers to the process by which eggs are removed from the ovary and matured in a lab before fertilization. This can be helpful for patients with polycystic ovarian syndrome and other hormonal disorders and those who produce too many immature follicles during ovarian stimulation.

One complication that can arise during IVM is egg “vitrification,” or freezing. Ice crystals can form on the outside when an egg is frozen and damage the cell membrane. This can make it impossible to fertilize and implant the egg once it is thawed.

However, scientists have developed a more effective method of vitrifying eggs called PRISM (Preimplantation Screening & In-vitro Maturation) in recent years. PRISM allows fertility doctors to freeze immature eggs while they are still inside egg follicles on the ovary surface. This technique improves cell survival rates upon thawing and can also reduce the costs of IVF.

INVOcel

INVOcell is a new device that allows couples undergoing IVF to use their own body as an incubator for their embryo. This process is called INVOcell vaginal incubation and is a natural alternative to traditional IVF procedures. The INVOcell is used as a vaginal incubator for up to five days after being inserted into the vagina. The woman will be able to go about her daily activities while the egg undergoes incubation. After five days, the egg can be retrieved from the INVOcell and either be transferred into the woman’s uterus or frozen for future use.

More Single Births

New technology and procedures allow for more single births rather than multiple births through IVF. This is beneficial to the mother and child, as there is a lower potential for complications during the pregnancy and delivery. The main reason behind this increase has been due to better laboratory techniques — namely, time-lapse embryo monitoring.

Dual Triggering:

This is when two drugs are administered simultaneously to women undergoing IVF to ensure ovulation. The result is a higher egg count, which means a better chance of conception.

Source, https://picukinews.com/recent-advancements-in-ivf-technology/